141214-18-8 Usage
Uses
Different sources of media describe the Uses of 141214-18-8 differently. You can refer to the following data:
1. An isopropyl ether derivative of the anesthetic Propofol (P829750).
2. Propofol Isopropyl Ether (Propofol EP Impurity G; Propofol USP Related Compound C) is an isopropyl ether derivative of the anesthetic Propofol (P829750).
Check Digit Verification of cas no
The CAS Registry Mumber 141214-18-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,2,1 and 4 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 141214-18:
(8*1)+(7*4)+(6*1)+(5*2)+(4*1)+(3*4)+(2*1)+(1*8)=78
78 % 10 = 8
So 141214-18-8 is a valid CAS Registry Number.
141214-18-8Relevant articles and documents
Commercial manufacturing of propofol: Simplifying the isolation process and control on related substances
Pramanik, Chinmoy,Kotharkar, Sandeep,Patil, Pradip,Gotrane, Dinkar,More, Yogesh,Borhade, Ajit,Chaugule, Balaji,Khaladkar, Tushar,Neelakandan,Chaudhari, Ashok,Kulkarni, Mukund G.,Tripathy, Narendra K.,Gurjar, Mukund K.
, p. 152 - 156 (2014/05/20)
A commercially viable manufacturing process for propofol (1) is described. The process avoids acid-base neutralization events during isolation of intermediate, 2,6-di-isopropylbenzoic acid (3) and crude propofol, and thus simplifies the synthesis on industrial scale to a considerable extent. Syntheses of five impurities/related substances (USP and EP) are also described.
