141223-71-4

Basic information

• Product Name: BENZYLOXYCARBONYL-L-VALYL-L-LYSYL-L-METHIONINE 4-METHYLCOUMARYL-7-AMIDE HYDROCHLORIDE
• Synonyms: PROTEASOME SUBSTRATE IV (FLUOROGENIC);N-CBZ-VAL-LYS-MET 7-AMIDO-4-METHYLCOUMARIN;Z-VKM-AMC;Z-VAL-LYS-MET-AMC;Z-VAL-LYS-MET-AMC ACETATE SALT;Z-VAL-LYS-MET-MCA HYDROCHLORIDE;BENZYLOXYCARBONYL-L-VALYL-L-LYSYL-L-METHIONINE 4-METHYLCOUMARYL-7-AMIDE HYDROCHLORIDE;z-val-lys-met 7-amido-4-methylcoumarin
• CAS NO: 141223-71-4
• Molecular Formula: C34H45N5O7S
• Molecular Weight: 667.82
• Product Categories: Amyloid A4-generating enzymes;Amyloid A4-generating enzymesEnzyme Substrates;Enzyme Substrates;Protease Substrates;Substrates by Enzyme
• Mol File: 141223-71-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 966.2±65.0 °C(Predicted)
• Appearance: /
• Density: 1.245±0.06 g/cm3(Predicted)
• Storage Temp.: −20°C
• PKA: 11.05±0.46(Predicted)
• CAS DataBase Reference: BENZYLOXYCARBONYL-L-VALYL-L-LYSYL-L-METHIONINE 4-METHYLCOUMARYL-7-AMIDE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYLOXYCARBONYL-L-VALYL-L-LYSYL-L-METHIONINE 4-METHYLCOUMARYL-7-AMIDE HYDROCHLORIDE(141223-71-4)
• EPA Substance Registry System: BENZYLOXYCARBONYL-L-VALYL-L-LYSYL-L-METHIONINE 4-METHYLCOUMARYL-7-AMIDE HYDROCHLORIDE(141223-71-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 141223-71-4(Hazardous Substances Data)

Usage

Uses

Fluorogenic Proteasome Substrate (Z-VKM-AMC) is used to measure the peptidase activity of the 20S proteasome. Also used as a fluorogenic substrate for Alzheimer''s Disease amyloid A4-generating enzymes. AMC has an excitation maximum of 340-360nm and an emission maximum of 440-460nm.