141237-50-5

Basic information

• Product Name: HIV-1 REV PROTEIN (34-50)
• Synonyms: HIV-1 REV PROTEIN (34-50);H-THR-ARG-GLN-ALA-ARG-ARG-ASN-ARG-ARG-ARG-ARG-TRP-ARG-GLU-ARG-GLN-ARG-OH;THR-ARG-GLN-ALA-ARG-ARG-ASN-ARG-ARG-ARG-ARG-TRP-ARG-GLU-ARG-GLN-ARG;HIV-1 rev Protein
• CAS NO: 141237-50-5
• Molecular Formula: C97H173N51O24
• Molecular Weight: 2437.74
• Mol File: 141237-50-5.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: -15°C
• CAS DataBase Reference: HIV-1 REV PROTEIN (34-50)(CAS DataBase Reference)
• NIST Chemistry Reference: HIV-1 REV PROTEIN (34-50)(141237-50-5)
• EPA Substance Registry System: HIV-1 REV PROTEIN (34-50)(141237-50-5)

Safety Data

• Hazardous Substances Data: 141237-50-5(Hazardous Substances Data)

Usage

Description

HIV-1 REV PROTEIN (34-50) is a crucial small fragment derived from the human immunodeficiency virus type 1 (HIV-1) protein known as REV. This segment is integral to the virus's replication and infectivity, as it contains a nuclear localization signal that aids in the export of unspliced and singly-spliced viral mRNAs from the nucleus to the cytoplasm. The understanding of its chemical properties and structure is vital for the development of targeted therapies and vaccines against HIV-1.

Uses

Used in Pharmaceutical Research and Development:
HIV-1 REV PROTEIN (34-50) is used as a research tool for studying the mechanisms of viral replication and mRNA export in HIV-1. It is instrumental in the development of antiviral drugs and vaccines targeting the HIV-1 virus.
Used in Drug Design:
This fragment is utilized in the design of drugs that can inhibit the function of the full-length REV protein, thereby disrupting the virus's ability to replicate and spread.
Used in Vaccine Development:
HIV-1 REV PROTEIN (34-50) is used as an immunogen in the creation of vaccines that aim to elicit an immune response against HIV-1, providing protection against infection.
Used in Diagnostics:
This protein fragment can be employed in diagnostic assays to detect the presence of HIV-1 or to monitor the effectiveness of treatments by assessing the levels of REV protein in infected individuals.
Used in Biochemical and Structural Studies:
HIV-1 REV PROTEIN (34-50) is used in biochemical and structural studies to understand the interactions between the protein and other cellular components, which can provide insights into the virus's life cycle and potential therapeutic targets.
Used in Molecular Biology:
This fragment is applied in molecular biology techniques to investigate the regulation of gene expression and the transport of viral mRNA, contributing to a broader understanding of the molecular mechanisms of HIV-1 infection.