141243-74-5

Basic information

• Product Name: (+)-(1R,2R)-2,7,7-Trimethyl-3-oxabicyclo<4.1.1>octan-4-one
• Synonyms: (+)-(1R,2R)-2,7,7-Trimethyl-3-oxabicyclo<4.1.1>octan-4-one
• CAS NO: 141243-74-5
• Molecular Weight: 168.236
• Mol File: 141243-74-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+)-(1R,2R)-2,7,7-Trimethyl-3-oxabicyclo<4.1.1>octan-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-(1R,2R)-2,7,7-Trimethyl-3-oxabicyclo<4.1.1>octan-4-one(141243-74-5)
• EPA Substance Registry System: (+)-(1R,2R)-2,7,7-Trimethyl-3-oxabicyclo<4.1.1>octan-4-one(141243-74-5)

Safety Data

• Hazardous Substances Data: 141243-74-5(Hazardous Substances Data)

Upstream product

• 473-62-1 (1S,5R)-2,6,6-Trimethyl-bicyclo[3.1.1]heptan-3-one 

Relevant articles and documents

The Baeyer-Villiger reaction of pinanones (bicyclo[3.1.1]heptanones)

The Baeyer-Villiger reaction of bicyclo[3.1.1]heptanones yields the expected lactones, but with some difficulty. These lactones readily react with alcohols, including the ethanol present in commercial chloroform, to give the corresponding hydroxy esters. Pinocamphone and isopinocamphone exhibit conformational control in the Baeyer-Villiger reaction, the trans-isomer yielding mainly the expected lactone, the cis-isomer (isopinocamphone) yielding hydroxyisopinocamphone. The use of this pathway as a synthetic route to cyclobutane monoterpenoids is discussed.