141247-29-2Relevant academic research and scientific papers
Identification of novel allosteric nonpeptidergic inhibitors of the human cytomegalovirus-encoded chemokine receptor US28
Vischer, Henry F.,Hulshof, Janneke W.,Hulscher, Saskia,Fratantoni, Silvina A.,Verheij, Mark H.P.,Victorina, Jane,Smit, Martine J.,de Esch, Iwan J.P.,Leurs, Rob
experimental part, p. 675 - 688 (2010/04/29)
Human cytomegalovirus (HCMV) is a widespread human pathogen, possessing onco-modulatory properties. Constitutive signaling of the HCMV-encoded chemokine receptor US28 and its ability to bind a broad spectrum of chemokines might facilitate HCMV-associated
