141278-35-5Relevant articles and documents
Reaction of N-methylisatoic anhydride with acetylenic amines: Formation of oxazoles and quinazolinones. Part 19: Acetylenic chemistry
Reisch,Usifoh,Okoh,Oluwadiya
, p. 18 - 20 (2007/10/02)
Reaction of N-methylisatoic anhydride (1) with acetylenic amines 2a-c gave acetylenic amides 3a-c. Base-catalyzed cyclization of 3a-c using potassium hydroxide in ethanol gave the corresponding oxazoles 5a-c. Upon treatment of 3a-c with formaldehyde the c