141306-11-8 Usage
Indole derivative
A modified version of the indole structure
1H-Indole, 5-fluoro-3-(4-fluorophenyl)is derived from the indole structure, which is a core structure found in various biologically active compounds.
Two fluorine atoms
Presence of fluorine atoms at specific positions
The compound has two fluorine atoms attached to the indole ring, specifically at the 5 and 4 positions, which can influence its reactivity, stability, and pharmacological properties.
Phenyl group attachment
A benzene ring structure connected to the indole ring
Medicinal chemistry and drug development potential
Possible applications in creating new drugs
Due to its structural features and biological activities, 1H-Indole, 5-fluoro-3-(4-fluorophenyl)may have potential applications in the field of medicinal chemistry and drug development.
Pharmacological properties
Ability to interact with biological systems
The compound may exhibit pharmacological properties, meaning it could interact with biological systems and potentially be used as a therapeutic agent.
Synthetic intermediate
A building block in the manufacturing of pharmaceuticals and agrochemicals
1H-Indole, 5-fluoro-3-(4-fluorophenyl)could serve as a synthetic intermediate, which is a compound used in the synthesis of other compounds, such as pharmaceuticals and agrochemicals.
Industrial and scientific utility
Potential applications in various fields
Further research into the properties and potential applications of 1H-Indole, 5-fluoro-3-(4-fluorophenyl)could reveal its utility in different industrial and scientific fields, expanding its potential uses and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 141306-11-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,3,0 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 141306-11:
(8*1)+(7*4)+(6*1)+(5*3)+(4*0)+(3*6)+(2*1)+(1*1)=78
78 % 10 = 8
So 141306-11-8 is a valid CAS Registry Number.
141306-11-8Relevant academic research and scientific papers
Synthesis and antimycobacterial activity of 3-phenyl-1h-indoles
Abbadi, Bruno Lopes,Basso, Luiz Augusto,Bizarro, Cristiano Valim,Dornelles, Maiele,Duarte, Lovaine,Etchart, Renata Jardim,Lourega, Rogério Vescia,Macchi, Fernanda Souza,Machado, Pablo,Neves, Christiano Ev,Perelló, Marcia Alberton,Rambo, Raoní S.,Silva, Fernanda Fries,Sperotto, Nathalia
, (2021/08/31)
Tuberculosis has been described as a global health crisis since the 1990s, with an estimated 1.4 million deaths in the last year. Herein, a series of 20 1H-indoles were synthesized and evaluated as in vitro inhibitors of Mycobacterium tuberculosis (Mtb) g
3-ARYLINDOLE COMPOUNDS
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, (2008/06/13)
3-Arylindole or 3-arylindazole derivatives having formula: STR1 wherein Ar is optionally substituted phenyl or a heteroaromatic group; R. sup.1-R 4 are independently selected from hydrogen, halogen, alkyl, alkoxy, hydroxy, nitro, alkylthio, alkylsulphonyl
Selective, Centrally Acting Serotonin 5-HT2 Antagonists. 2. Substituted 3-(4-Fluorophenyl)-1H-indoles
Andersen, Kim,Perregaard, Jens,Arnt, Joern,Nielsen, Joern Bay,Begtrup, Mikael
, p. 4823 - 4831 (2007/10/02)
A series of 3-(4-fluorophenyl)-1H-indoles substituted in the 1-position with 4-piperidinyl, 1,2,3,6-tetrahydro-4-pyridinyl, and 4-piperazinyl was synthesized. By variation of the substituents in the benzene part of the indole nucleus in 1-2-4-3-(4-fluo