1413432-55-9Relevant academic research and scientific papers
Diastereoselective and enantioselective desymmetrization of α-substituted cyclohexadienones via intramolecular stetter reaction
Jia, Min-Qiang,Liu, Chuan,You, Shu-Li
, p. 10996 - 11001 (2012)
Highly diastereoselective and enantioselective desymmetrization of α-substituted cyclohexadienones via NHC-catalyzed intramolecular Stetter reaction was realized. Amino-indanol derived triazolium salt bearing a C 6F5 group was found to be the optimal catalyst precursor in the intramolecular Stetter reaction furnishing tricyclic products bearing multi-stereocenters in up to 96% yield and >99% ee.
