141346-32-9Relevant academic research and scientific papers
Reactions of Enamines with Dehydro Aromatic Compounds
Gingrich, Henry L.,Huang, Qiurong,Morales, Angel L.,Jones, Maitland
, p. 3803 - 3806 (2007/10/02)
Benzyne reacts with enamines through a combination of ene and 2 + 2 cycloadditions.One of the two possible ene reactions is greatly favored.The three-dimensional intermediate, 1,2-dehydro-o-carborane, eschews the 2 + 2 reaction in favor of the ene reaction that is less favored in the benzyne reactions.This preference is rationalized in terms of the different steric demands of the two intermediates.
