1413576-43-8

Basic information

• Product Name: 2-(benzyl(5-(benzyl(2-(cyclohexylamino)-2-oxoethyl)amino)pentyl)amino)-N-(3,4,5-trimethoxyphenyl)acetamide
• Synonyms: 2-(benzyl(5-(benzyl(2-(cyclohexylamino)-2-oxoethyl)amino)pentyl)amino)-N-(3,4,5-trimethoxyphenyl)acetamide
• CAS NO: 1413576-43-8
• Molecular Weight: 644.855
• Mol File: 1413576-43-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(benzyl(5-(benzyl(2-(cyclohexylamino)-2-oxoethyl)amino)pentyl)amino)-N-(3,4,5-trimethoxyphenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzyl(5-(benzyl(2-(cyclohexylamino)-2-oxoethyl)amino)pentyl)amino)-N-(3,4,5-trimethoxyphenyl)acetamide(1413576-43-8)
• EPA Substance Registry System: 2-(benzyl(5-(benzyl(2-(cyclohexylamino)-2-oxoethyl)amino)pentyl)amino)-N-(3,4,5-trimethoxyphenyl)acetamide(1413576-43-8)

Safety Data

• Hazardous Substances Data: 1413576-43-8(Hazardous Substances Data)

Upstream product

• 41640-76-0 N¹,N⁵-dibenzylpentane-1,5-diamine 
• 50-00-0 formaldehyd 
• 931-53-3 Cyclohexyl isocyanide 
• 1413576-40-5 2-(benzyl(5-(benzylamino)pentyl)amino)-N-(3,4,5-trimethoxyphenyl)acetamide 

Relevant articles and documents

An efficient synthesis of symmetric and unsymmetric bis-(β- aminoamides) via Ugi multicomponent reaction

A library of symmetrical and unsymmetrical bis-(β-aminoamides) has been prepared starting from symmetrical secondary diamines by using a double Ugi four-component reaction. A sacrifical Mumm rearrangement, thanks to the use of 2-hydroxymethyl benzoic acid, is necessary to suppress the competing split-Ugi reaction, increasing the yield and simplifying the purification step. The scope, the reaction conditions, and the role of water in trapping the nitrilium intermediate are also discussed.