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141363-21-5

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141363-21-5 Usage

Type

Chemical compound
With antiretroviral and antiviral properties

Common usage

Treatment of HIV infection
Often used in combination with other medications

Mechanism of action

Inhibition of reverse transcriptase enzyme
Essential for the replication of the HIV virus

Effect on the body

Reduction of viral load and slowing down disease progression
Improves the quality of life for patients

Activity against other viruses

Herpes simplex and cytomegalovirus

Administration

Oral intake
Available in the form of tablets or capsules

Check Digit Verification of cas no

The CAS Registry Mumber 141363-21-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,3,6 and 3 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 141363-21:
(8*1)+(7*4)+(6*1)+(5*3)+(4*6)+(3*3)+(2*2)+(1*1)=95
95 % 10 = 5
So 141363-21-5 is a valid CAS Registry Number.

141363-21-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[(E)-2,3-dihydroinden-1-ylidenemethyl]-1-methyl-5-nitroimidazole

1.2 Other means of identification

Product number -
Other names 1H-Imidazole,2-((2,3-dihydro-1H-inden-1-ylidene)methyl)-1-methyl-5-nitro

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:141363-21-5 SDS

141363-21-5Downstream Products

141363-21-5Relevant articles and documents

S(RN)1 synthesis of new 5-nitroimidazoles highly active against protozoa and anaerobes

Vanelle,Crozet,Maldonado,Barreau

, p. 167 - 178 (2007/10/02)

1-Methyl-2-chloromethyl-5-nitroimidazole reacts by an S(RN)1 mechanism with various aliphatic, cyclic or heterocyclic nitronate anions to afford, in high yields, new 5-nitroimidazoles bearing a trisubstituted ethylenic double bond at the 2 position. Some of these compounds are as active as metronidazole in vitro and in vivo against protozoa and anaerobic bacteria. Structure-activity relationships are discussed.

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