1413732-47-4

Basic information

• Product Name: (2,2'-bipyridine)Cu(SCF3)
• Synonyms: (2,2'-bipyridine)Cu(SCF3);Trifluoromethylthiolato(2,2-bipyridine)copper(I), 97%
• CAS NO: 1413732-47-4
• Molecular Formula: C₁₁H₈CuF₃N₂S
• Molecular Weight: 321.81
• Mol File: 1413732-47-4.mol
• Article Data: 5

Chemical Properties

• Appearance: red/crystal
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Sensitive: air sensitive, moisture sensitiv
• CAS DataBase Reference: (2,2'-bipyridine)Cu(SCF3)(CAS DataBase Reference)
• NIST Chemistry Reference: (2,2'-bipyridine)Cu(SCF3)(1413732-47-4)
• EPA Substance Registry System: (2,2'-bipyridine)Cu(SCF3)(1413732-47-4)

Safety Data

• Statements: 21/22-36/38
• Safety Statements: 26-36/37-60
• TSCA: No
• Hazardous Substances Data: 1413732-47-4(Hazardous Substances Data)

Usage

Uses

Novel, air-stable copper reagent for trifluoromethylthiolation of aryl halides.

Upstream product

• 10544-50-0 sulfur 
• 366-18-7 [2,2]bipyridinyl 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 3872-23-9 Copper(I) trifluoromethanethiolate 

Downstream Products

• 80783-57-9 1-tert-butyl-4-[(trifluoromethyl)sulfanyl]benzene 
• 352-68-1 4-trifluoromethylthiotoluene 
• 177551-63-2 [1,1′-biphenyl]-4-yl(trifluoromethyl)sulfane 
• 713-67-7 1-{4-[(trifluoromethyl)sulfanyl]phenyl}ethan-1-one 
• 240408-91-7 1-(2-((trifluoromethyl)thio)phenyl)ethanone 
• 332-26-3 4-[(trifluoromethyl)sulphanyl]benzenecarbonitrile 
• 660-44-6 3-[(trifluoromethyl)thio]benzonitrile 
• 773873-91-9 methyl 2-((trifluoromethyl)thio)benzoate 
• 403-66-7 p-nitrophenyl trifluoromethyl sulfide 
• 458-06-0 1-[(trifluoromethyl)thio]-3,4-dichlorobenzene 
• 78914-94-0 4-methoxyphenyl trifluoromethylsulfide 
• 57830-49-6 2-(trifluoromethylthio)pyridine 

Relevant articles and documents

Cu-mediated oxidative trifluoromethylthiolation of arylboronic acids with (bpy)CuSCF3

An efficient trifluoromethylthiolation reaction of arylboronic acids with (bpy)CuSCF3in the presence of oxygen at room temperature is described. This method produces a variety of aryl trifluoromethylthioether derivatives in good to high yield. The mechanism of this trifluoromethylthiolation is discussed as well.

Development of Multigram Scale Synthesis of Trifluoromethylthiolating Reagent: (bpy)CuSCF3

A practical and reproducible procedure for the efficient preparation of (bpy)CuSCF3 (1), a copper reagent for trifluoromethylthiolation reaction, is reported. All reaction parameters were optimized, and reagent 1 was synthesized in 26 g scale.

An air-stable copper reagent for nucleophilic trifluoromethylthiolation of aryl halides

A series of copper(I) trifluoromethyl thiolate complexes have been synthesized from the reaction of CuF2 with Me3SiCF 3 and S8 (see scheme; Cu red, F green, N blue, S yellow). These air-stable complexes serve as reagents for the efficient conversion of a wide range of aryl halides into the corresponding aryl trifluoromethyl thioethers in excellent yields. Copyright