141381-76-2

Basic information

• Product Name: 2-Propenamide, 3-(4-methoxyphenyl)-N-(phenylmethyl)-
• CAS NO: 141381-76-2
• Molecular Formula: C17H17NO2
• Molecular Weight: 267.327
• Mol File: 141381-76-2.mol

Chemical Properties

• CAS DataBase Reference: 2-Propenamide, 3-(4-methoxyphenyl)-N-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenamide, 3-(4-methoxyphenyl)-N-(phenylmethyl)-(141381-76-2)
• EPA Substance Registry System: 2-Propenamide, 3-(4-methoxyphenyl)-N-(phenylmethyl)-(141381-76-2)

Safety Data

• Hazardous Substances Data: 141381-76-2(Hazardous Substances Data)

Upstream product

• 830-09-1 3-(4'-methoxyphenyl)propenoic acid 
• 100-46-9 benzylamine 

Relevant articles and documents

AMIDATION METHOD AND ESTERIFICATION METHOD USING SULFONIC ACID HALIDE

PROBLEM TO BE SOLVED: To provide a safe and economical method for rapidly synthesizing amides and esters in high yield. SOLUTION: There is provided a method for amidating an amine or a derivative thereof using a sulfonic acid halide, where a sulfonic acid halide is allowed to act as an activator on a carboxylic acid or a derivative thereof to synthesize an active ester, and the active ester is reacted with an amine or a derivative thereof as a nucleophile to amidate the amine or the derivative thereof to obtain a corresponding amide or a derivative thereof. In a similar manner, a sulfonic acid halide is allowed to act as an activator on a carboxylic acid or a derivative thereof to synthesize an active ester, and the active ester is reacted with an alcohol or a derivative thereof as a nucleophile to esterify the alcohol or the derivative thereof to obtain a corresponding ester or a derivative thereof. SELECTED DRAWING: Figure 1 COPYRIGHT: (C)2016,JPO&INPIT

The use of BrCCl3-PPh3 in Appel type transformations to esters, O-acyloximes, amides, and acid anhydrides

Esters, acyloximes, amides and acid anhydrides have been prepared from the respective carboxylic acids, oximes, amines and alcohols by the use of the reagent combination BrCCl3-PPh3. The reactions obviate the handling acyl halides or more aggressive reagents PCl3, POCl3, or SOCl2. Furthermore, the environmentally hazardous CCl4 used in Appel-type reactions is replaced with BrCCl3, a reagent of less environmental concern.

1-(o-NITROPHENYLSULPHONYLOXY)BENZOTRIAZOLE, REAGENT FOR THE CONDENSATION OF CARBOXYLIC ACIDS WITH AMINES

With the Schotten-Baumann reaction we have synthesized 1-(o-nitrophenylsulfonyloxy)benzotriazole and have shown its suitability for the synthesis of esters of 1-hydroxybenzotriazole and carboxylic amides, and also of peptides.