141401-25-4

Upstream product

• 141401-24-3 4-(3-hydroxypropoxy)butyl 2-tetrahydropyranyl ether 
• 98-59-9 p-toluenesulfonyl chloride 
• 51326-51-3 4-(tetrahydropyran-2-yloxy)butan-1-ol 
• 141401-23-2 3-[4-(Tetrahydro-pyran-2-yloxy)-butoxy]-propionaldehyde 
• 141401-22-1 4-(2-cyanoethoxy)butyl 2-tetrahydropyranyl ether 

Downstream Products

• 141401-34-5 N-methyl-2'-<(2-cyanoethyl)thio>-<4-(3-p-toluenesulfonyloxy)propoxy>butananilide 
• 141401-15-2 4-[3-(Toluene-4-sulfonyloxy)-propoxy]-butyric acid 

Relevant academic research and scientific papers

PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE

The present invention provides a compound represented by formula [I] shown below or a pharmaceutically acceptable salt thereof that has an inhibitory effect on 20-HETE producing enzyme. (in formula [I] above, the structure represented by formula [II] below: represents any of the structures represented by formula group [III] below: R1, R2, R3, and R4 independently represent a hydrogen atom, a fluorine atom, methyl, or the like, R5 represents any of the structures represented by formula group [IV]:

Medium-membered ring ketone synthesis. Synthesis of oxa- and aza-cyclooctanone derivatives

As a model study on the synthesis of natural products possessing an eight-membered cyclic ether or amine framework such as laurencin (1) and FR900482 (6), two kinds of 2-benzyl oxacyclooctanones (7 and 8) and 2-methyl azacyclooctanones (9 and 10) were syn