141437-99-2

Upstream product

• 135949-90-5 [2-((S)-2-tert-Butoxycarbonylamino-4-methylsulfanyl-butyldisulfanylmethyl)-3-phenyl-propionylamino]-acetic acid benzyl ester 
• 141437-87-8 2-(2-Carboxy-3-phenyl-propyldisulfanylmethyl)-3-phenyl-propionic acid 
• 141437-88-9 {2-[2-(Benzyloxycarbonylmethyl-carbamoyl)-3-phenyl-propyldisulfanylmethyl]-3-phenyl-propionylamino}-acetic acid benzyl ester 
• 81110-69-2 N-(2-mercaptomethyl-3-phenyl-1-oxopropyl)-glycine benzyl ester 
• 141437-96-9 [(S)-3-Methylsulfanyl-1-(pyridin-2-yldisulfanylmethyl)-propyl]-carbamic acid tert-butyl ester 
• 139429-04-2 Thioacetic acid S-((S)-2-tert-butoxycarbonylamino-4-methylsulfanyl-butyl) ester 
• 141437-94-7 ((S)-1-Mercaptomethyl-3-methylsulfanyl-propyl)-carbamic acid tert-butyl ester 

Downstream Products

• 135949-61-0 [2-((S)-2-Amino-4-methanesulfinyl-butyldisulfanylmethyl)-3-phenyl-propionylamino]-acetic acid benzyl ester 

Relevant academic research and scientific papers

NOVEL AMINO ACID DERIVATIVES, METHOD FOR PREPARING SAME, AND THERAPEUTIC USE THEREOF

The disclosure relates to novel compounds of the formula (I) R1NH—CH(R2)CH2—S—S—CH2—C(R3)(R4)—CONH—C(R5)(R6)—COOR7, in which R1 is a (acyloxy)alk

"Mixed Inhibitor-Prodrug" as a New Approach toward Systemically Active Inhibitors of Enkephalin-Degrading Enzymes

In order to evaluate the possible advantages of potentiating the effects of the endogenous enkephalins, to obtain analgesia without the serious drawbacks of morphine, it was essential to design systemically active compounds which inhibit the two metaboliz