141446-99-3

Basic information

• Product Name: 1,3-dihydro-6-phenylsulfonyl-5-(pyridin-2-ylthio)-2H-benzimidazole-2-spirocyclohexane
• CAS NO: 141446-99-3
• Molecular Weight: 437.587
• Mol File: 141446-99-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,3-dihydro-6-phenylsulfonyl-5-(pyridin-2-ylthio)-2H-benzimidazole-2-spirocyclohexane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dihydro-6-phenylsulfonyl-5-(pyridin-2-ylthio)-2H-benzimidazole-2-spirocyclohexane(141446-99-3)
• EPA Substance Registry System: 1,3-dihydro-6-phenylsulfonyl-5-(pyridin-2-ylthio)-2H-benzimidazole-2-spirocyclohexane(141446-99-3)

Safety Data

• Hazardous Substances Data: 141446-99-3(Hazardous Substances Data)

Upstream product

• 27429-80-7 spiro[2H-benzimidazole-2,1'-cyclohexane] 
• 3190-03-2 1,3-dihydrospiro[2H-benzimidazole-2,1'-cyclohexane] 
• 141421-18-3 1,3-dihydro-5-(pyridin-2thioyl)-2H-benzimidazole-2-spirocyclohexane 
• 873-55-2 sodium benzenesulfonate 
• 141421-23-0 5-(pyridin-2-ylthio)-2H-benzimidazole-2-spirocyclohexane 

Relevant articles and documents

2H-Benzimidazoles (Isobenzimidazoles). Part 6. Sulfur Derivatives

The products obtained by treating 2H-benzimidazole-2-spirocyclohexane 1 or its 5-chloro derivative 9 with various thiols (PrSNa, ButSNa, PhSNa, pyridine-2-thiol, or pyrimidine-2-thiol) depend on the reaction conditions.Monosubstitution is possible and any number of alkylthio groups can be introduced up to four. 5-Phenylsulfonyl- 18 and 5-nitro-2H-benzimidazole-2-spirocyclohexane 10 react with pyridine-2-thiol or pyrimidine-2-thiol in position-4 whilst the 5-(pyridin-2-ylthio) derivative 16 react with sodium benzenesulfinate in position-6.In all cases the products isolated were the 1,3-dihydro compounds 26, 38, 39 or 21, respectively.