141463-47-0

Upstream product

• 143122-12-7 (4S,5R)-3-(tert-butoxycarbonyl)-4-(cyclohexylmethyl)-2,2-dimethyloxazolidine-5-methanol 
• 124577-55-5 (4S,5S)-3-(tert-butoxycarbonyl)-4-(cyclohexylmethyl)-2,2-dimethyloxazolidine-5-ethanol 
• 145341-80-6 (4S,5S)-3-(tert-butoxycarbonyl)-4-cyclohexylmethyl-5-formylmethyl-2,2-dimethyl-1,3-oxazolidine 
• 143122-13-8 (4S,5R)-3-(tert-butoxycarbonyl)-4-(cyclohexylmethyl)-5-<(mesyloxy)methyl>-2,2-dimethyloxazolidine 
• 124577-56-6 (4S,5S)-3-(tert-butoxycarbonyl)-4-(cyclohexylmethyl)-5-<2-(mesyloxy)ethyl>-2,2-dimethyloxazolidine 
• 143122-33-2 (4S,5S)-3-(tert-butoxycarbonyl)-4-(cyclohexylmethyl)-2,2-dimethyl-5-<(2-pyridylthio)methyl>oxazolidine 
• 25024-53-7 Boc-His(Dnp)-OH 
• 104882-44-2 (2S,3S)-2-(tert-butoxycarboxamido)-1-cyclohexyl-5-hexen-3-ol 
• 143122-11-6 (4S,5S)-5-allyl-3-(tert-butoxycarbonyl)-4-(cyclohexylmethyl)-2,2-dimethyloxazolidine 
• 121533-55-9 (4S,5S)-3-tert-butoxycarbonyl-4-cyclohexylmethyl-2,2-dimethyl-5-vinyloxazolidine 
• 117997-58-7 tert-butyl (4S,5R)-4-(cyclohexylmethyl)-5-formyl-2,2-dimethyl-3-oxazolidinecarboxylate 
• 2637-34-5 2-Sulfanylpyridine 
• 141463-15-2 [(1S,2R)-1-Cyclohexylmethyl-2-hydroxy-3-(pyridin-2-ylsulfanyl)-propyl]-carbamic acid tert-butyl ester 
• 1053628-52-6 (2R,3S)-3-Amino-4-cyclohexyl-1-(pyridin-2-ylsulfanyl)-butan-2-ol 

Relevant academic research and scientific papers

Renin inhibitors containing new P1-P1' dipeptide mimetics with heterocycles in P1'

A series of renin inhibitors containing new P1-P1' dipeptide mimetics are presented. The P1-P1' mimetics were obtained from (4S,5S)-3-(tert- butoxycarbonyl)-4-(cyclohexylmethyl)-5-[(ω-mesyloxy)alkyl]-2,2- dimeth

Renin inhibitors containing C-termini derived from mercaptoheterocycles

A series of transition-state analogues having heterocyclythio C-termini has been synthesized and evaluated for inhibition of human renin. Addition of mercaptoheterocycles to a chiral Boc-amino epoxide intermediate led, after several steps, to the target [