1414774-97-2Relevant academic research and scientific papers
Enantioselective synthesis of cryptopleurine and boehmeriasin A via organocatalytic intramolecular aza-Michael addition
Zeng, Chuanqi,Liu, Hanbin,Zhang, Mengyao,Guo, Jiajia,Jiang, Shunchao,Yu, Shouyun
supporting information, p. 2251 - 2254,4 (2020/07/31)
The enantioselective synthesis of phenanthroquinolizidine alkaloids cryptopleurine and boehmeriasin A was achieved in eight steps from commercial available Cbz-protected 2-piperidinone in 22% and 20% overall yield, respectively. The key steps of this route are intramolecular enantioselective aza-Michael addition, intramolecular aldol addition, and oxidative coupling.
