141478-00-4Relevant articles and documents
A facile synthesis of pyrrolo-(di)-benzazocinones via an intramolecular N-acyliminium ion cyclisation
King, Frank D.,Aliev, Abil E.,Caddick, Stephen,Tocher, Derek A.,Courtier-Murias, Denis
experimental part, p. 167 - 177 (2009/04/07)
A facile, moderate to high yielding synthesis of hexahydro-(di)- benzazocinones is described via an intramolecular N-acyliminium ion cyclisation. The iminium ion intermediates are formed from the readily available 4,4-diethoxybutyl amides with an excess of triflic acid. For electron-withdrawing substituents, better yields were obtained from the pre-formed 2-hydroxypyrrolidine amides. From NMR studies, at ambient temperatures the pyrrolo-benzazocin-3-ones exist as a slowly equilibrating mixture of two conformations.
The synthesis and antilipidperoxidation activity of 4,4-diarylbutylamines and 4,4-diarylbutanamides
Miyano,Tatsuoka,Suzuki,Imao,Satoh,Ishihara,Hirotsu,Kihara,Hatta,Horikawa,Sumoto
, p. 1570 - 1574 (2007/10/02)
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