1414854-08-2Relevant academic research and scientific papers
Synthesis of functionalized 2-aryl-4-(indol-3-yl)-4H-chromenes via iodine-catalyzed domino Michael addition-intramolecular cyclization reaction
Yin, Guodong,Fan, Ling,Ren, Tianbing,Zheng, Chunyang,Tao, Qing,Wu, Anxin,She, Nengfang
, p. 8877 - 8883 (2013/01/15)
An efficient synthesis of novel functionalized 2-aryl-4-(indol-3-yl)-4H- chromenes has been developed, in the presence of a catalytic amount of iodine, from easily available starting materials, 2-hydroxychalcone derivatives. Indole, substituted indoles and 7-azaindole are suitable for this transformation. The possible domino Michael addition-intramolecular cyclization reaction mechanism is proposed.
