1414932-17-4Relevant academic research and scientific papers
Palladium-catalyzed intermolecular domino reaction of gem-dibromoenynes with anilines; A one-pot synthesis of quinolines and quinolinones
Meng, Tianhao,Zhang, Wen-Xiong,Zhang, Hui-Jun,Liang, Yun,Xi, Zhenfeng
, p. 2754 - 2762 (2012)
An efficient domino process involving palladium-catalyzed amination of an alkenyl bromide, 1,5-H transfer, annulation via 6-exo-dig electrophilic cyclization, and palladium-catalyzed etherification, is described. This reaction provides an efficient one-pot synthesis of multi-substituted quinolines and quinolinones from gem-dibromoenynes and anilines. Georg Thieme Verlag Stuttgart New York.
