1414941-72-2Relevant academic research and scientific papers
Metal-free catalyzed oxidative trimerization of indoles by using TEMPO in air: A biomimetic approach to 2-(1H-indol-3-yl)-2,3′-biindolin-3-ones
Qin, Wen-Bing,Chang, Qiong,Bao, Yun-Hong,Wang, Ning,Chen, Zheng-Wang,Liu, Liang-Xian
, p. 8814 - 8821,8 (2012)
A simple, convenient and efficient metal-free catalyzed oxidative trimeric reaction of indoles toward a variety of 2-(1H-indol-3-yl)-2,3′-biindolin- 3-one derivatives in moderate to excellent yields has been developed. This transformation proceeds via a tandem oxidative homocoupling reaction by using TEMPO in air as an environmentally benign oxidant. This methodology provides an alternative approach for the direct generation of all-carbon quaternary centers at the C3 position of indoles. This journal is
