1414941-81-3Relevant academic research and scientific papers
Metal-free-catalyzed oxidative trimerization of indoles using NaNO 2 to construct quaternary carbon centers: Synthesis of 2-(1H-Indol-3-yl)-2,3′-biindolin-3-ones
Xue, Jun,Bao, Yunhong,Qin, Wenbing,Zhu, Jiayi,Kong, Yubo,Qu, Hongen,Chen, Zhengwang,Liu, Liangxian
, p. 2215 - 2221 (2014)
A simple, convenient, and efficient synthesis of 2-(1H-indol-3-yl)-2, 3′-biindolin-3-one derivatives via a transition-metal-free-catalyzed oxidative trimeric reaction of indoles has been developed. This transformation may have occurred through a tandem oxidative homocoupling reaction by using NaNO2 in pyridine as oxidant. This methodology provides an alternative approach for the direct generation of all-carbon quaternary centers at the C2 position of indoles. Copyright
Copper-catalyzed oxidative trimerization of indoles by using TEMPO to construct quaternary carbon centers: The synthesis of 2-(1 H -indol-3-yl)-2,3′-biindolin-3-ones
Kong, Yu-Bo,Zhu, Jia-Yi,Chen, Zheng-Wang,Liu, Liang-Xian
supporting information, p. 269 - 273 (2014/05/06)
A simple, convenient, and efficient synthesis of 2-(1H-indol-3-yl)-2, 3′-biindolin-3-one derivatives has been developed by the oxidative trimeric reaction of indoles using the TEMPO/CuCl2 catalyst system under ambient air. This methodology provides an alternative approach for the direct generation of all-carbon quaternary centers at the C-2 position of indoles.
