1414960-66-9Relevant articles and documents
1-((1H-PYRAZOL-4-YL)METHYL)-3-(PHENYL)-1,3-DIHYDRO-2H-IMIDAZOL-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS GPR139 ANTAGONISTS FOR THE TREATMENT OF E.G. DEPRESSION
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Paragraph 000416-000417, (2021/11/26)
The present invention refers to compounds of formula (I). The present invention also relates to compounds of formula (I) for use as G Protein coupled Receptor 139 (GPR139) antagonists in methods of medical treatment of e.g. depression, Alzheimer's disease
A Unified Strategy for the Synthesis of β-Carbolines, γ-Carbolines, and Other Fused Azaheteroaromatics under Mild, Metal-Free Conditions
Uredi, Dilipkumar,Motati, Damoder Reddy,Blake Watkins
supporting information, p. 6336 - 6339 (2018/10/15)
An efficient, unified approach for the synthesis of β-carbolines, γ-carbolines, and other fused azaheteroaromatics has been realized under metal-free conditions, from propargylic amines and (hetero)aromatic aldehydes. This unified strategy provides β- and
Cascade electrophilic iodocyclization: Efficient preparation of 4-iodomethyl substituted tetrahydro-β-carbolines and formal synthesis of oxopropaline G
Song, Hongjian,Liu, Yongxian,Wang, Qingmin
supporting information, p. 3274 - 3277 (2013/07/26)
4-Iodomethyl substituted tetrahydro-β-carbolines, the core structure of numerous natural products and bioactive molecules, are readily prepared via I2-promoted cascade electrophilic cyclization. The reactivity differences of olefins and alkynes