1414973-13-9

Upstream product

• 108-94-1 cyclohexanone 
• 104-88-1 4-chlorobenzaldehyde 
• 109-77-3 malononitrile 
• 1867-38-5 4-chlorobenzylidenemalonodinitrile 

Downstream Products

• 1414973-17-3 5-(4-chlorophenyl)-6,7,8,9-tetrahydropyrimido[4,5-b]quinolin-4(3H, 5H, 10H)-one 
• 1414973-21-9 5-(4-chlorophenyl)-6,7,8,9-tetrahydro-2-methylpyrimido[4,5-b]quinolin-4(3H, 5H, 10H)-one 
• 1414973-25-3 5-(4-chlorophenyl)-5,6,7,8,9,10-hexahydropyrimido[4,5-b]quinoline-2,4(1H, 3H)-dithione 
• 1414973-29-7 5-(4-chlorophenyl)-3,4,5,6,7,8,9,10-octahydro-4-imino-3-phenylpyrimido[4,5-b]quinoline-2(1H)-thione 
• 1414973-33-3 3-n-butyl-5-(4-chlorophenyl)-3,4,5,6,7,8,9,10-octahydro-4-iminopyrimido[4,5-b]quinoline-2(1H)-thione 
• 1414973-37-7 ethyl N-[4-(4-chlorophenyl)-3-cyano-1,4,5,6,7,8-hexahydroquinolin-2-yl]formimidate 
• 1414973-41-3 4-amino-5-(4-chlorophenyl)-5,6,7,8,9,10-hexahydropyrimido[4,5-b]quinoline 
• 1414973-45-7 3-amino-5-(4-chlorophenyl)-3,4,6,7,8,9-hexahydro-4-imino-5H, 10H-pyrimido[4,5-b]quinoline 
• 1414973-49-1 3-(4-chlorobenzylideneamino)-5-(4-chlorophenyl)-3,4,6,7,8,9-hexahydro-4-imino-5H,10H-pyrimido[4,5-b]quinoline 
• 1414973-53-7 5-(4-chlorophenyl)-3,4,6,7,8,9-hexahydro-4-imino-3-(3,4-dimethoxybenzylideneamino)-5H,10H-pyrimido[4,5-b]quinoline 
• 1414973-57-1 12-(4-chlorophenyl)-7,8,9,10,11,12-hexahydro-[1,2,4]triazolo[2',3':3,4]pyrimido[6,5-b]quinoline 
• 1414973-61-7 5-(4-chlorophenyl)-3-(ethoxycarbonylamino)-4-(ethoxycarbonylimino)-3,4,6,7,8,9-hexahydro-5H,10H-pyrimido[4,5-b]quinoline 

Relevant academic research and scientific papers

Synthesis of hexahydro-4-phenylquinoline-3-carbonitriles using Fe3O4@SiO2-SO3H nanoparticles as a superior and retrievable heterogeneous catalyst under ultrasonic irradiations

An efficient synthesis of hexahydro-4-phenylquinoline-3-carbonitriles is described by the four-component condensation reaction of cyclohexanone, ammonium acetate, malononitrile, and aromatic aldehydes using Fe3O4@SiO2-SO3H nanoparticles as a superior and retrievable heterogeneous catalyst under ultrasonic irradiations. The reusability of the catalyst and little catalyst loading, excellent yields, short reaction times, using the sonochemical procedure as a green process and an alternative energy source are some benefits of this method.

Synthesis and antitumor screening of new series of pyrimido-[4,5-b] quinolines and [1,2,4]triazolo[2′,3′:3,4]pyrimido[6,5-b]quinolines

New series of pyrimido[4,5-b]quinolines and [1,2,4]triazolo[2′, 3′:3,4]pyrimido[6,5-b]quinolines have been synthesized. Compounds 4a, 4e, 4f, 4h, 5b, 5d, 6a, 6d, 6e, 8c, 8d, 10c-e, 10h, 11a, 11b, and 12a were tested for in vitro antitumor activity against