141501-54-4Relevant articles and documents
A VERSATILE NEW METHOD FOR SYNTHESIS OF ISOQUINOLINES; 6,8-DIHYDROXYISOQUINOLINE DERIVATIVES FROM 6-METHYL-1,3-OXAZIN-4-ONES
Yamamoto, Yutaka,Morita, Yasuo,Ohmukai, Osamu
, p. 515 - 518 (2007/10/02)
A versatile method for synthesis of isoquinolone derivatives (4a-h) from 2-substituted 6-methyl-4H-1,3-oxazin-4-ones (1a-h) is described.Transformation of 1a-h with diethyl acetonedicarboxylate (2) in the presence of potassium tert-butoxide afforded 6-sub