1415087-04-5Relevant articles and documents
Structure-activity relationships and blood distribution of antiplasmodial aminopeptidase-1 inhibitors
Deprez-Poulain, Rebecca,Flipo, Marion,Piveteau, Catherine,Leroux, Florence,Dassonneville, Sandrine,Florent, Isabelle,Maes, Louis,Cos, Paul,Deprez, Benoit
, p. 10909 - 10917 (2013/03/14)
Malaria is a severe infectious disease that causes between 655 000 and 1.2 million deaths annually. To overcome the resistance to current drugs, new biological targets are needed for drug development. Aminopeptidase M1 (PfAM1), a zinc metalloprotease, has