14152-57-9

Upstream product

• 6479-18-1 1-methyl-2(1H)-quinoxalinone 
• 98807-33-1 4-Methyl-benzoic acid (3aR,4R,6R,6aR)-6-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester 
• 4760-34-3 N-methyl-1,2-phenylenediamine 
• 14152-56-8 2-ethoxycarbonylmethylene-3-oxo-1,2,3,4-tetrahydroquinoxaline 
• 74-88-4 methyl iodide 

Relevant academic research and scientific papers

The Cross-Dehydrogenative Coupling Reaction of β-Ketoesters with Quinoxalin-2(1H)-ones

The cross-dehydrogenative coupling (CDC) reaction of β-ketoesters with quinoxalin-2(1H)-one derivatives has been successfully performed by using a readily available Cu salt as the catalyst in moderate to excellent yields under mild conditions. Owing to the characteristic of handy operation and good functional group tolerance, this protocol affords a convenient access to α-quinoxalinone-substituted β-ketoesters. Preliminary mechanistic investigations show this transformation possibly underwent an unusual ionic pathway.