1415212-06-4Relevant academic research and scientific papers
Nickel-catalyzed C–P cross-coupling of (het)aryl tosylates with secondary phosphine oxides
He, Xiao-Yun
, p. 747 - 752 (2021/02/26)
A novel and convenient approach to the synthesis of various tertiary phosphine oxides via nickel-catalyzed cross-coupling of (het)aromatic tosylates with secondary phosphine oxides is developed. The reaction employs cheap nickel as the catalyst, 1-(2-(di-tert-butylphosphanyl)phenyl)-4-methoxypiperidine (L3) as the ligand, and pyridine as the base. This reaction produces the corresponding (het)aromatic phosphorus compounds in good to high yields. Moreover, four new tertiary phosphine oxides are reported in this process.
Efficient copper(I)-catalyzed coupling of secondary phosphine oxides with aryl halides
Stankevi?, Marek,W?odarczyk, Adam
, p. 73 - 81 (2013/01/15)
A catalytic system has been developed for the efficient synthesis of tertiary arylphosphine oxides by coupling of readily available secondary phosphine oxides with aryl bromides or iodides in the presence of copper(I) iodide as a catalyst and (S)-α-phenylethylamine as a ligand. The system exhibits high activity in the coupling of secondary diaryl-, alkylaryl- and dialkylphosphine oxides.
