1415226-39-9

Basic information

• Product Name: 5-(3-Chlorophenyl)-3-Methoxypicolinonitrile
• Synonyms: 5-(3-Chlorophenyl)-3-Methoxypicolinonitrile
• CAS NO: 1415226-39-9
• Molecular Formula: C₁₃H₉ClN₂O
• Molecular Weight: 244.67636
• Mol File: 1415226-39-9.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(3-Chlorophenyl)-3-Methoxypicolinonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-Chlorophenyl)-3-Methoxypicolinonitrile(1415226-39-9)
• EPA Substance Registry System: 5-(3-Chlorophenyl)-3-Methoxypicolinonitrile(1415226-39-9)

Safety Data

• Hazardous Substances Data: 1415226-39-9(Hazardous Substances Data)

Usage

General Description

5-(3-Chlorophenyl)-3-Methoxypicolinonitrile is a chemical compound with the molecular formula C12H8ClNO. It is a nitrile derivative and a member of the picolinonitrile family of compounds. This chemical is commonly used as an intermediate in organic synthesis and is known for its potential applications in pharmaceutical and agrochemical industries. It is a yellow solid at room temperature and is soluble in organic solvents. 5-(3-Chlorophenyl)-3-Methoxypicolinonitrile is also known for its role as a building block in the synthesis of various bioactive molecules and is commonly utilized in research and development processes.

Upstream product

• 16063-70-0 2,3,5-trichloropyridine 
• 823-56-3 2-Fluoro-3,5-dichloropyridine 
• 67-56-1 methanol 
• 1415226-38-8 5-(3-chlorophenyl)-3-chloro-2-cyanopyridine 
• 85331-33-5 2-Cyano-3,5-dichloropyridine 
• 63503-60-6 3-chlorophenylboronic acid 
• 124-41-4 sodium methylate 

Downstream Products

• 1000025-36-4 5-(3-chlorophenyl)-3-hydroxy-pyridine-2-carboxylic acid carbamoylmethyl-amide 
• 1000025-07-9 {[5-(3-chloro-phenyl)-3-hydroxy-pyridine-2-carbonyl]-amino}-acetic acid 
• 1415226-40-2 5-(3-chlorophenyl)-3-hydroxypyridine-2-carboxylic acid 

Relevant articles and documents

MANUFACTURING PROCESS FOR 3,5-DICHLOROPICOLINONITRILE FOR SYNTHESIS OF VADADUSTAT

Disclosed herein are methods and processes of preparing vadadustat or a pharmaceutically acceptable salts thereof, and intermediates (e.g., a compound of Formula (I), (I-F), (II), or (IV), or a pharmaceutically acceptable salts thereof) useful for the syn

PROCESS FOR PREPARING 2-[[5-(3-CHLOROPHENYL)-3-HYDROXYPYRIDINE-2-CARBONYL]AMINO]ACETIC ACID

Disclosed herein are methods and processes of preparing vadadustat and pharmaceutically acceptable salts thereof, and intermediates of formula (I) and their salts useful for the synthesis of vadadustat.

PROCESS FOR PREPARING [(3-HYDROXYPYRIDINE-2-CARBONYL)AMINO]ALKANOIC ACIDS, ESTERS AND AMIDES

Disclosed are processes for preparing [(3-hydroxypyridine-2-carbonyl)amino]-alkanoic acids, derivatives, inter alia, 5-aryl substituted and 5-heteroaryl substituted [(3-hydroxypyridine-2-carbonyl]aminolacetic acids. Further disclosed are methods for making prodrugs of [(3-hydroxypyridine-2-carbonyl)-amino]acetic acids, for example, [(3-hydroxypyridine-2-carbonyl]amino}acetic acid esters and {[3-hydroxypyridine-2-carbonyl]amino}acetic acid amides. The disclosed compounds are useful as prolyl hydroxylase inhibitors or for treating conditions wherein prolyl hydroxylase inhibition is desired.