1415228-86-2Relevant academic research and scientific papers
Riccardin C derivatives as anti-MRSA agents: Structure-activity relationship of a series of hydroxylated bis(bibenzyl)s
Sawada, Hiromi,Okazaki, Miki,Morita, Daichi,Kuroda, Teruo,Matsuno, Kenji,Hashimoto, Yuichi,Miyachi, Hiroyuki
, p. 7444 - 7447 (2013/02/21)
Members of a series of macrocyclic bis(bibenzyl) riccardin-class derivatives were found to exhibit antibacterial activity towards methicillin-resistant Staphylococcus aureus (anti-MRSA activity). Structure-activity relationship (SAR) studies were conducted, focusing on the number and position of the hydroxyl groups. The minimum essential structure for anti-MRSA activity was also investigated.
