1415256-80-2Relevant academic research and scientific papers
Straightforward synthesis of non-natural chalcogen peptides via ring opening of aziridines
Schwab, Ricardo S.,Schneider, Paulo H.
, p. 10449 - 10455,7 (2012/12/13)
The synthesis of new chiral non-natural seleno-, thio-, and telluro-peptides is described herein. These new compounds were prepared through simple and brief synthetic route, from inexpensive and commercially available amino acids. The products, possessing a highly modular character, were obtained in good to excellent yields (50-96%), via ring opening of aziridines with chalcogenolate anions, generated using indium(I) iodide as a reducing agent.
