1415261-82-3Relevant academic research and scientific papers
Metal-free intramolecular aminofluorination of alkenes mediated by PhI(OPiv)2/hydrogen fluoride-pyridine system
Wang, Qing,Zhong, Wenhe,Wei, Xiong,Ning, Maoheng,Meng, Xiangbao,Li, Zhongjun
supporting information, p. 8566 - 8569 (2013/01/15)
A convenient, metal-free intramolecular aminofluorination of alkenes has been developed. Employing readily available PhI(OPiv)2 and hydrogen fluoride-pyridine in the presence of BF3·OEt2, tosyl-protected pent-4-en-1-amines were converted to 3-F-piperidines in one step in good yields as well as high stereoselectivity.
