1415308-48-3Relevant academic research and scientific papers
Synthesis of N-alkyl and N-aryl isoquinolones and derivatives via Pd-catalysed C-H activation and cyclization reactions
Zhang, Nana,Li, Binyao,Zhong, Hongban,Huang, Jianhui
, p. 9429 - 9439 (2013/01/15)
Relatively less expensive Pd-catalysed oxidative coupling reactions for the preparation of N-alkyl and N-aryl substituted isoquinolones and their derivatives have been developed. A broad reaction scope has been demonstrated. In addition, studies of the reaction additives and mechanistic insights, as well as KIE studies for a better understanding of the reaction pathway, have been discussed.
