1415320-98-7Relevant academic research and scientific papers
A complementary approach to 3,5-substituted pyrazoles with tosylhydrazones and terminal alkynes mediated by TfOH
Liu, Ping,Xu, Qian-Qian,Dong, Chao,Lei, Xinsheng,Lin, Guo-Qiang
supporting information, p. 2087 - 2092 (2012/11/07)
A complementary method for the preparation of 3,5-substituted pyrazoles in moderate to high yields has been explored via TfOH-induced addition of tosylhydrazones to the terminal alkynes. This acid-induced addition procedure might be an operationally safe alternative compared to typical 1,3-dipolar cycloaddition as there is no involvement of diazo compounds.
