1415335-87-3Relevant academic research and scientific papers
Chemoselective Two-Directional Reaction of Bifunctionalized Substrates: Formal Ketal-Selective Mukaiyama Aldol Type Reaction
Yanai, Hikaru,Sasaki, Yuichi,Yamamoto, Yuki,Matsumoto, Takashi
supporting information, p. 2457 - 2461 (2015/10/19)
In the presence of an acidic zwitterion bearing a highly stabilized carbanion, reactions of ω,ω-dialkoxy carbonyl compounds with ketene silyl acetals (KSA) resulted in an unusual molecular transformation; substitution reaction with the KSA at the ketal mo
Lewis acid catalyzed intramolecular condensation of ynol ether-acetals. synthesis of alkoxycycloalkene carboxylates
Tran, Vincent,Minehan, Thomas G.
, p. 6100 - 6103 (2013/02/26)
Treatment of ynol ether-tethered dialkyl acetals with catalytic quantities of scandium triflate in CH3CN gives rise to five-, six-, and seven-membered alkoxycycloalkene carboxylates in good to excellent yields. Tri- and tetrasubstituted carbocyclic and heterocyclic alkenes may be formed by this method, and the products obtained may serve as useful intermediates for natural product synthesis.
