1415351-72-2

Upstream product

• 10254-60-1 4-fluorophenyl(methyl)carbamothioic chloride 
• 459-59-6 4-fluoro-N-methylaniline 
• 1415351-60-8 S-but-3-en-2-yl 1H-imidazole-1-carbothioate 

Downstream Products

• 1558811-72-5 S-2-(4-fluorophenyl)but-3-en-2-yl methylcarbamothioate 
• 1558812-01-3 (R)-S-2-(4-fluorophenyl)but-3-en-2-yl methylcarbamothioate 
• 1558812-27-3 2-(4-fluorophenyl)but-3-ene-2-thiol 

Relevant academic research and scientific papers

Tertiary thiols from allylic thiocarbamates by tandem enantioselective [3,3]-sigmatropic rearrangement and stereospecific arylation

The synthesis of tertiary thiols in enantiomerically enriched form is accomplished by lithiation of enantiomerically enriched N-aryl allylic thiocarbamates. Formation of an allyllithium derivative promotes intramolecular N to C aryl migration to the posit

S-allyl thiocarbamates from allylic alcohols by in situ [3,3]-sigmatropic rearrangement of a thiocarbonyldiimidazole adduct

Treatment of allylic alcohols with thiocarbonyldiimidazole generates an unstable O-allyl imidazolyl thione ester, which rearranges spontaneously and in high yield to the corresponding S-allyl imidazolyl thiol ester. Displacement of the imidazole by N-alky