1415414-08-2Relevant academic research and scientific papers
Efficient, one-pot, BF3·OEt2-mediated synthesis of substituted N-aryl lactams
Chaturvedi, Devdutt,Chaturvedi, Amit K.,Mishra, Nisha,Mishra, Virendra
, p. 2627 - 2630,4 (2012/12/12)
A quick, efficient, one-pot, BF3·OEt2-mediated synthesis of substituted N-aryl lactams in good to excellent yields by reaction of various substituted arenes with a variety of ω-azido alkanoic acid chlorides at room temperature is reported.
An efficient and novel approach for the synthesis of substituted N-aryl lactams
Chaturvedi, Devdutt,Chaturvedi, Amit K.,Mishra, Nisha,Mishra, Virendra
, p. 9148 - 9151,4 (2012/12/12)
A quick, efficient, one-pot method for the synthesis of substituted N-aryl lactams through the reaction of various kinds of corresponding substituted arenes with a variety of ω-azido alkanoic acid chlorides using a Lewis acid (i.e. EtAlCl2) at room temperature, through the in situ involvement of a Friedel-Crafts reaction followed by intramolecular Schimdt rearrangement was developed, and afforded good to excellent yields.
