141554-61-2 Usage
Molecular structure
A derivative of papaverine with a tetrahydroisoquinoline core, a methyl group at the 1-position, and phenylmethoxy groups at the 6 and 7 positions. A phenylmethyl group is attached to the 2-position.
Pharmacological and biological properties
R-tetrahydropapaverine has potential in treating erectile dysfunction and other smooth muscle-related disorders due to its vasodilatory effects, which relax the smooth muscles and increase blood flow. It also has potential applications in cardiovascular and neurological research.
Sedative and analgesic properties
R-tetrahydropapaverine has been researched for its potential as a sedative and analgesic agent and has shown promise in preclinical studies.
Dopamine receptor modulation
R-tetrahydropapaverine has the ability to modulate dopamine receptors and neurotransmission, which could have implications for the treatment of various neurological and psychiatric disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 141554-61-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,5,5 and 4 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 141554-61:
(8*1)+(7*4)+(6*1)+(5*5)+(4*5)+(3*4)+(2*6)+(1*1)=112
112 % 10 = 2
So 141554-61-2 is a valid CAS Registry Number.
141554-61-2Relevant academic research and scientific papers
Synthesis of the R and S enantiomers of 1,2,3,4-tetrahydro-6,7-dihydroxy-1-methylisoquinoline-1-carboxylic acid
Dostert, P,Varasi, M,Torre, A Della,Monti, C,Rizzo, V
, p. 57 - 59 (2007/10/02)
1,2,3,4-Tetrahydro-6,7-dihydroxy-1-methylisoquinoline-1-carboxylic acid (salsolinol-1-carboxylic acid) has been shown to be a bioprecursor of (R)-salsolinol in humans.We report here a synthesis and the determination of the absolute configurations of both