1415547-10-2

Upstream product

• 32462-30-9 (S)-hydroxyphenylglycine 
• 1415547-09-9 (S)-methyl 2-(4-hydroxyphenyl)-2-(methoxycarbonylamino)acetate 

Downstream Products

• 1415547-29-3 (S)-ethyl 3-(1-(4-(hex-5-enyloxy)phenyl)-2-hydroxyethylamino)-2,2-dimethyl-3-oxopropanoate 
• 1415547-15-7 (S)-3-(1-(4-(hex-5-enyloxy)phenyl)-2-hydroxyethylamino)-2,2-dimethyl-3-oxopropanoic acid 
• 1415547-11-3 (S)-methyl 1-(4-(hex-5-enyloxy)phenyl)-2-hydroxyethyl carbamate 
• 1415547-12-4 (S)-4-(4-(hex-5-enyloxy)phenyl)oxazolidin-2-one 
• 1415547-07-7 (S)-2-amino-2-(4-(hex-5-enyloxy)phenyl)ethanol 

Relevant academic research and scientific papers

Synthesis of a C1-symmetric Box macrocycle and studies towards active-template synthesis of mechanically planar chiral rotaxanes

A C1-symmetric Box macrocycle has been synthesized for the first time. The Box macrocycle along with other C1 and C 2-symmetric Box ligands were evaluated and compared as ligands in the Cadiot-Chodkiewicz, oxidative Heck and CuAAC 'click' reactions as part of our studies towards achieving active-metal template synthesis of mechanically planar chiral rotaxanes. This study constitutes the first report of Cadiot-Chodkiewicz and CuAAC 'click' reactions using Box ligands, as well as the first dedicated study of oxidative Heck reactions using Box ligands.