1415560-69-8

Basic information

• Product Name: PF 02341066 hydrochloride
• Synonyms: Crizotinib (hydrochloride);PF 02341066 hydrochloride;PF-02341066 hydrochloride;Crizotinib HCl,PF-02341066 HCl;3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine hydrochloride;Crizotinib HCl;3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine:hydrochloride
• CAS NO: 1415560-69-8
• Molecular Formula: C21H23Cl3FN5O
• Molecular Weight: 486.7976232
• Product Categories: MET
• Mol File: 1415560-69-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: PF 02341066 hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: PF 02341066 hydrochloride(1415560-69-8)
• EPA Substance Registry System: PF 02341066 hydrochloride(1415560-69-8)

Safety Data

• Hazardous Substances Data: 1415560-69-8(Hazardous Substances Data)

Usage

General Description

PF 02341066 hydrochloride, also known as crizotinib, is a chemical compound that is used in the treatment of non-small cell lung cancer. It works as a selective inhibitor of anaplastic lymphoma kinase (ALK) and the c-ros oncogene 1 (ROS1) receptor tyrosine kinases, which are known to be involved in the growth and proliferation of cancer cells. By blocking the activity of these kinases, PF 02341066 hydrochloride helps to slow down or stop the progression of cancer, making it a promising targeted therapy for patients with specific genetic mutations. Additionally, PF 02341066 hydrochloride is also being studied for its potential in treating other types of cancer, such as inflammatory myofibroblastic tumors and neuroblastoma.