1415586-02-5Relevant articles and documents
An efficient preparation of N-acetyl enamides catalyzed by Ru(II) complexes
Murugan, Kaliyappan,Huang, Da-Wei,Chien, Yu-Ting,Liu, Shiuh-Tzung
, p. 268 - 273 (2013/01/15)
Reductive acetylation of ketoximes to give the corresponding acyl enamides can be achieved by using 1-3 mol % of [RuCl2(p-cymene)]2 as the catalyst in the presence of KI as the reducing agent in high yields. This procedure has been applied to synthesize N-[1-(1,3-benzodioxol-5-yl)-1-butenyl] acetamide (6), which is the intermediate for the synthesis of DMP 777, an inhibitor of leukocyte elastase.