141564-25-2Relevant academic research and scientific papers
Nitrosation of 2-Amino-2-deoxy-D-galactitol; a Model Experiment for the Study of Reduced Oligosaccharides derived from Mucus Glycoproteins
Carter, Steven R.,Williams, J. Michael,Clamp, John R.
, p. 2775 - 2778 (2007/10/02)
Sequential nitrosation, and reduction with sodium cyanoborohydride, of 2-amino-2-deoxy-D-galactitol gave, as major products, 2-deoxy-D-lyxo- (and/or -xylo-)hexitol (39percent) and glycerol (43percent).Minor products included a hexitol and diastereoisomeric 2-deoxy-2-hydroxymethyl-D-pentitols (provisionally identified).Reduction of the nitrosation products with sodium borodeuteride gave 2-deoxy-D-hexitols with more deuterium at C-3 than at C-1.Glycerol was also shown to be a product of the nitrosation and reduction of 2-amino-2-deoxy-D-glucitol.The implications of these results for the nitrosation of the 2-amino-2-deoxy-D-galactitol-containing oligosaccharides derived from mucus glycoproteins are discussed.
