1415801-95-4Relevant academic research and scientific papers
Nickel-catalyzed C-P cross-coupling of diphenylphosphine oxide with aryl chlorides
Zhang, Hong-Yu,Sun, Meng,Ma, Yan-Na,Tian, Qiu-Ping,Yang, Shang-Dong
, p. 9627 - 9633 (2013/01/16)
A novel protocol for the preparation of various diarylphosphine oxide compounds via a Ni-catalyzed cross-coupling of aryl chlorides with R 2P(O)H has been developed. Notably, this process exhibits the following very attractive features: (i) the process is simpler and operates under mild reaction conditions; (ii) the process is generally cheaper in part because the more accessible aryl chloride is used to form the C-P bond; (iii) the process avoids the need for simultaneous preparation and use of Ar 2P(O)M. The Royal Society of Chemistry 2012.
