1415816-87-3Relevant academic research and scientific papers
Interactions of the antitumor macrolide aplyronine a with actin and actin-related proteins established by its versatile photoaffinity derivatives
Kita, Masaki,Hirayama, Yuichiro,Yamagishi, Kota,Yoneda, Kozo,Fujisawa, Ryosuke,Kigoshi, Hideo
, p. 20314 - 20317 (2013/02/23)
The antitumor and apoptogenic macrolide aplyronine A (ApA) is a potent actin-depolymerizing agent. We developed an ApA acetylene analog that bears the aryldiazirine group at the C34 terminus, which formed a covalent bond with actin. With the use of the ph
