1415888-05-9

Basic information

• Product Name: C₁₈H₁₇N₇O₆
• Synonyms: C₁₈H₁₇N₇O₆
• CAS NO: 1415888-05-9
• Molecular Weight: 427.376
• Mol File: 1415888-05-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₁₇N₇O₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₁₇N₇O₆(1415888-05-9)
• EPA Substance Registry System: C₁₈H₁₇N₇O₆(1415888-05-9)

Safety Data

• Hazardous Substances Data: 1415888-05-9(Hazardous Substances Data)

Upstream product

• 31010-69-2 7-(methoxycarbonyl)pterine 
• 658-79-7 N-Gly-Tyr 

Relevant articles and documents

Peptide-conjugated pterins as inhibitors of ricin toxin A

Several 7-peptide-substituted pterins were synthesized and tested as competitive active-site inhibitors of ricin toxin A (RTA). Focus began on dipeptide conjugates, and these results further guided the construction of several tripeptide conjugates. The binding of these compounds to RTA was studied via a luminescence-based kinetic assay, as well as through X-ray crystallography. Despite the relatively polar, solvent exposed active site, several hydrophobic interactions, most commonly π-interactions not predicted by modeling programs, were identified in all of the best-performing inhibitors. Nearly all of these compounds provide IC50 values in the low micromolar range.