1415893-19-4Relevant articles and documents
A general phosphoric acid-catalyzed desymmetrization of meso-aziridines with silylated selenium nucleophiles
Senatore, Matilde,Lattanzi, Alessandra,Santoro, Stefano,Santi, Claudio,Sala, Giorgio Della
, p. 6205 - 6207 (2011)
The first example of meso-aziridine desymmetrization with selenium nucleophiles is reported. The reaction, promoted by VAPOL-hydrogen phosphate using (phenylseleno)trimethylsilane as the nucleophile, proves to be very general and highly enantioselective (84-99% ee).