1415903-26-2Relevant academic research and scientific papers
On the proposed structures and stereocontrolled synthesis of the cephalosporolides
Tlais, Sami F.,Dudley, Gregory B.
, p. 1287 - 1292 (2012/09/22)
The synthesis of four candidate stereoisomers of cephalosporolide H is described, made possible by a zinc-chelation strategy for controlling the stereochemistry of oxygenated 5,5-spiroketals. The same strategy likewise enables the first stereocontrolled synthesis of cephalosporolide E, which is typically isolated and prepared admixed with its spiroketal epimer, cephalosporolide F.
