1415916-32-3Relevant academic research and scientific papers
Synthesis of novel tetrahydro-1H-pyrazolo[4,3-c]pyridines via intramolecular nitrilimine cycloaddition
Garofalo, Albert William,Jagodzinski, Jacek Jerzy,Konradi, Andrei William,Ng, Raymond Anthony,Semko, Christopher Michael,Sham, Hing Leung,Sun, Minghua,Ye, Xiaocong Michael
, p. 1063 - 1066 (2012/10/07)
The preparation of novel tetrahydro-1H-pyrazolo[4,3-c]pyridines is reported. Pivotal to the synthesis of these compounds was the development of mild reaction conditions to generate a highly functionalized nitrilimine capable of undergoing an intramolecular cycloaddition with a tethered alkyne. The desired cycloadduct was formed as an equal mixture of diastereomers.
