1415922-56-3Relevant articles and documents
Diastereo- and enantioselective asymmetric hydrogenation of α-amido-β-keto phosphonates via dynamic kinetic resolution
Tao, Xiaoming,Li, Wanfang,Li, Xiaoming,Xie, Xiaomin,Zhang, Zhaoguo
supporting information, p. 72 - 75 (2013/03/28)
Dynamic kinetic resolution of various α-amido-β-keto phosphonates via asymmetric hydrogenation proceeded efficiently to give the corresponding β-hydroxy-α-amido phosphonates in high diastereo- and enantioselectivities (up to 99:1 syn/anti, 99.8% ee). The addition of catalytic amounts of CeCl3 3 7H2O is necessary to achieve both good selectivity and catalytic efficiency under mild reaction conditions.